| Abstract Detail
Molecular Ecology and Evolution Quandt, Dietmar [1], Wanke, Stefan [1], Müller, Kai [2], Hernández-Maqueda, Rafa [3], Stech, Michael [4], Löhne, Cornelia [5], Worberg, Andreas [5], Hilu, Khidir W. [6], Borsch, Thomas [5]. The role of hairpins in molecular evolution. FAST evolving genomic regions often display impressive degrees of length variation. Although these regions are widely used in phylogenetic analyses, their mutational dynamics and resulting patterns of variability are still incompletely understood. Microstructural changes are analysed in several datasets with dense sampling for bryophytes (trnT-F, psbT-H, atpB-rbcL) or basal angiosperms (trnT-F, petD, trnK/matK) and compared across land plants (trnT-F, psbT-H, trnK/matK). It appears that inversions are largely associated with hairpins. Depending on their structural positions, inversions are often highly homoplastic unlike other kinds of microstructural changes (e.g., simple sequence repeats). Utilizing secondary structures and minimum free energy models, slipped-strand mispairing as a potential mechanism that creates duplications is evaluated for different structural situations and a modified mechanism for complex repeats is proposed.
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Related Links:
1 - Dresden University of Technology, Institute of Botany, Plant Phylogenetics & Phylogenomics Group, Dresden, D-01062, Germany
2 - Pennsylvania State University, Department of Biology, Institute of Molecular Evolutionary Genetics, and The Huck Institutes of the Life Sciences, University Park, Pennsylvania, 16802, USA
3 - Real Jardin Botánico (CSIC), Plaza de Murillo 2, Madrid, E-28014
4 - Freie Universität Berlin, Institut für Biologie, - Systematische Botanik und Pflanzengeographie, Altensteinstraße 6, Berlin, D-14195, Germany
5 - Rheinische Friedrich-Wilhelms-Universität Bonn, Nees-Institut für Biodiversität der Pflanzen, Meckenheimer Allee 170, Bonn, D-53115, Germany
6 - Virginia Polytechnic Institute and State University, Department of Biology, Blacksburg, Virginia, 24061, USA
Keywords:
Inversions
indels
simple sequence repeats
slipped-strand mispairing.
Presentation Type: Oral Paper:Papers for Topics
Session: 26-11
Location: 350/Holt
Date: Monday, July 31st, 2006
Time: 4:30 PM
Abstract ID:738 |
